前期 火曜日 ３講時 川北キャンパスＣ２０３. 単位数/Credit(s): 2. 担当教員(所属)/Instructor (Position): 市之瀬 敏晴、岡本 泰典、工藤 雄大、千葉 杏子、村越 ふみ、奥村 正樹、ASEEL MARAHLEH、松林 英明、佐藤 伸一 所属：学際科学フロンティア研究所. 対象学部/Object: 国際学士コース(＊). 開講期/Term: ３セメスター. 科目群/Categories: 全学教育科目学術基礎科目-基礎生物学. 履修年度: 2024. 科目ナンバリング/Course Numbering: ZDB-BIO102E. 使用言語/Language Used in Course: 英語.
各学部の履修内規または学生便覧を参照。
Biology B
Cells are the structural and functional units of living organisms. Understanding basics of cell biology is essential for studying all areas of life sciences and any related branches of natural sciences. The main objective of this course is to learn the essential principles of cell biology by learning how the living cells are made and operated from a molecular perspective: especially, how proteins including transmembrane proteins and enzymes work and how energy is obtained and used in living cells. Moreover, behavior of cells, such as cell migration, cell division and sexual reproduction will be also introduced. This course particularly emphasizes the structure and functions of cells and utilization of biochemical reactions in different biological processes.
Upon finishing this course, students will have a solid grasp of the basic biochemical components and their functions including proteins, membranes and metabolic pathways as well as dynamic cellular natures behind self-replication and maintenance. To accomplish this goal, students need to understand the basic of biochemistry of protein, membrane transport, metabolism, energy generation. In addition, by applying the concept of cell biology as well as biochemistry, students will learn more about living organisms including humans and will have a glimpse of cutting-edge sciences.
Some of the specific learning objectives include:
• Describe the different levels of protein structure and their functions
• Understand membrane and organelle dynamics
• Explain the basic principles of enzyme activity and catalysis
• Understand the fundamental role of central carbon and energy metabolism in
living systems
• Understand recombinant DNA technology
• Understand cellular processes like cell-cycle control and reproduction
• Appreciate the important connectivity among biomolecules and cellular processes
To achieve these objectives, students need to complete weekly reading and problem-set assignments. Quizzes and in-class exercises will be used to promote co-learning and interactions between students. In addition, a final examination will be used to evaluate student learning and ability to extend what they learned. We highly recommend students who have taken ‘Biology A’ to take this course. Together with ‘Biology A’, this course will cover the whole chapters in the textbook (Essential Cell Biology, ECB), and will provide comprehensive knowledge in basic cell biology and biochemistry. Students who did not take ‘Biology A’ are welcome, too.
1) Introduction
2) Protein structure (Chap. 4)
3) Protein function (Chap. 4)
4) Membrane structure (Chap.11)
5) Transmembrane transport (Chap.12)
6) Intracellular compartments & protein transport (Chap.15)
7) Metabolism (Glycolysis & Citric acid cycle) (Chap.13)
8) Metabolism (Glycolysis & Citric acid cycle) (Chap.13)
9) Energy generation in Mitochondria and Chloroplasts 1 (Chap. 14)
10) Energy generation in Mitochondria and Chloroplasts 2 (Chap.14)
11) Recombinant DNA technology (Chap. 10)
12) Cytoskeleton (Chap.17)
13) Cell cycle & division (Chap.18)
14) Sexual reproduction & genetics (Chap.19)
15) Final examination
Attendance and active participation (60%) and final examination (40%).
Students are expected to spend about 2-3 hours per week, reading relevant textbook material, preparing for the class and completing online assignments.
No
1) This is a general, entry-level biology course, open to all students and compulsory for first-year FGL students in the AMB program. High school-level familiarity with basic organic chemistry and biology is expected, but not necessary. Japanese students and exchange students from any fields are encouraged to enroll, knowing that this is an introductory course held in English.
2) Essential Cell Biology (ECB 4th or 5th Edition) is the main reference textbook.
3) Instructors are young researchers belonging to the Frontier Research Institute for Interdisciplinary Sciences (FRIS). They are available for questions and consultation via email or Google Classroom.