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有機化学概論A(AMC) / General Organic Chemistry A

後期 金曜日 2講時. 単位数/Credit(s): 2. 担当教員/Instructor : 水上 進. 学期/Semester: 後期. 開講年度/Year: 2024. 科目ナンバリング/Course code/number: SCH-ORG221E. 使用言語/Language Used in Course: 英語.

主要授業科目/Essential Subjects

所属講座等

Institute of Mulidisciplinary Research for Advanced Materials (IMRAM), Laboratory of Cell Functional Molecular Chemistry

授業題目

General Organic Chemistry A

Course Title

General Organic Chemistry A

授業の目的と概要

Objective and Summary of Class:
This class is part of organic chemistry classes, including Special Class in Basic Chemistry III, and General Organic Chemistry A, C, and D. The lecture covers the following topics:
(1) Basic chemistry of organic halides.
(2) Nucleophilic substitution reactions and reaction theory
(3) Diene and allylic systems
(4) Conjugated and aromatic compounds
(5) Aromatic substitution reactions
(6) Properties of alcohols, phenols, ethers, and thiols.

This class will provide the broad fundamentals of organic chemistry that are essential for students to be a chemist.

Purpose/Abstract

Objective and Summary of Class:
This class is part of organic chemistry classes, including Special Class in Basic Chemistry III, and General Organic Chemistry A, C, and D. The lecture covers the following topics:
(1) Basic chemistry of organic halides.
(2) Nucleophilic substitution reactions and reaction theory
(3) Diene and allylic systems
(4) Conjugated and aromatic compounds
(5) Aromatic substitution reactions
(6) Properties of alcohols, phenols, ethers, and thiols.

This class will provide the broad fundamentals of organic chemistry that are essential for students to be a chemist.

学習の到達目標

Goal of Study:
To understand
(1) Properties of alkyl halides and related compounds, synthetic methods, radical reactions, principles of the stability of allyl radicals, the characteristics of Grignard reactions
(2) Reactions of organic compounds, especially the characteristics and reaction mechanisms of nucleophilic substitutions and aliphatic reactions
(3) Stability of conjugated chains, electrophilic reactions, kinetic and thermodynamic control of reactions, and the characteristics of Diels-Alder reactions
(4) Structure of benzene and its derivatives, the principles of aromatic stability, heterocyclic aromatic compounds, the Huckel rule, and electrophilic substitution reactions
(5) Chemical properties and reactivity of alcohols, phenols, epoxides, and thiols

Goal

Goal of Study:
To understand
(1) Properties of alkyl halides and related compounds, synthetic methods, radical reactions, principles of the stability of allyl radicals, the characteristics of Grignard reactions
(2) Reactions of organic compounds, especially the characteristics and reaction mechanisms of nucleophilic substitutions and aliphatic reactions
(3) Stability of conjugated chains, electrophilic reactions, kinetic and thermodynamic control of reactions, and the characteristics of Diels-Alder reactions
(4) Structure of benzene and its derivatives, the principles of aromatic stability, heterocyclic aromatic compounds, the Huckel rule, and electrophilic substitution reactions
(5) Chemical properties and reactivity of alcohols, phenols, epoxides, and thiols

授業内容・方法と進度予定

Contents:
The class will involve chapters 10, 11, and 14–18 of Organic Chemistry 9th Ed. by John McMurry. However, the parts in chapter 14 covering spectroscopy will be omitted.

1. Introduction
2. Organohalides (Chapter 10)
3. Nucleophilic substitutions and eliminations (Chapter 11)
4. Conjugated compounds (Chapter 14)
5. Benzene and aromaticity (Chapters 15)
6. Electrophilic aromatic substitution (Chapter 16)
7. Alcohols and phenols (Chapter 17)
8. Ethers and epoxides; Thiols and Sulfides (Chapter 18)

Contentsandprogressscheduleofthe class

Contents:
The class will involve chapters 10, 11, and 14–18 of Organic Chemistry 9th Ed. by John McMurry. However, the parts in chapter 14 covering spectroscopy will be omitted.

1. Introduction
2. Organohalides (Chapter 10)
3. Nucleophilic substitutions and eliminations (Chapter 11)
4. Conjugated compounds (Chapter 14)
5. Benzene and aromaticity (Chapters 15)
6. Electrophilic aromatic substitution (Chapter 16)
7. Alcohols and phenols (Chapter 17)
8. Ethers and epoxides; Thiols and Sulfides (Chapter 18)

成績評価方法

Grading:
Evaluation will be performed on the basis of exams, class participation, and homework results.

Grading

Grading:
Evaluation will be performed on the basis of exams, class participation, and homework results.

教科書および参考書

McMurry Organic Chemistry 9th Ed.

Books required/referenced

McMurry Organic Chemistry 9th Ed.

授業時間外学習

Problem-solving exercise

Preparation and review

Problem-solving exercise

Remarks

Information on class implementation such as Google Classroom class code and ISTU link will be posted on the online class portal site of the Faculty of Science and Graduate School of Science.

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